Study of Placental Function in Healthy and Pathological Pregnancies

University of Colorado Denver (CU Denver)

Status: Enrolling

Conditions: Pregnancy

Study type: Observational

Funder types: Other

Identifiers

NCT02321007

14-1073

Details and patient eligibility

About

The purpose of this study is to establish a tissue and data repository consisting of samples of human placentas, umbilical cord blood, and maternal blood, collected at the time of delivery. Specimens will be used in cellular, molecular, and functional studies to learn more about changes in placental structure and function, which can result in serious pregnancy complications and determine life-long health by programming the fetus for future metabolic and cardiovascular disease.

Enrollment: 1,250 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy women delivering at term

• Women with pregnancy complications such as:

  • pre-term birth,
  • intrauterine growth restriction,
  • diabetes, and
  • obesity.

Exclusion criteria

• Women:

  • under stress,
  • experiencing pain of labor.

• Pregnancies complicated by other pathologies.