Study of Platelet Population Changes Under Circulatory Support With ECMO (ECMO-POP)

University Hospital, Strasbourg, France

Status: Enrolling

Conditions: Cardiac Failure; Respiratory Failure

Study type: Observational

Funder types: Other

Identifiers

NCT07334457

9614

Details and patient eligibility

About

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Enrollment: 75 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital.
• Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.

Exclusion criteria

• Subject who has expressed their opposition to participating in the study.
• Subject under legal protection.
• Subject under guardianship or curatorship.