Study of Psychosexual Impact of Cancer-Related Infertility in Women: Third Party Reproductive Assistance

Memorial Sloan Kettering Cancer Center (MSK)

Status: Completed

Conditions: Endometrial Cancer; Infertility; Uterine Cancer; Non-Hodgkin's Lymphoma; Vaginal Cancer; Leukemia; Cervical Cancer

Treatments: Behavioral: survey instrument

Study type: Observational

Funder types: Other

Identifiers

NCT00581646

06-110

Details and patient eligibility

About

This study aims to learn about the needs and feelings of women who are infertile. Being infertile means not being able to have a child without the help of a third party. There are other options for building a family. The researchers are interested in the participants' thoughts about these options and want to learn about the experiences of infertile women due to cancer treatment as well as women who are infertile due to other causes. The researchers hope that what they learn will allow them to better care for infertile women in the future.

Full description

As part of this study, you will be asked to fill out a series of questionnaires. These questions will ask about your feelings, sexual function, quality of life, and ideas about reproductive options. We will also ask some questions about you, your health, and your medical history. You can choose to answer these questions either at one of your doctor visits or over the telephone. You can decide the best way to complete this assessment.

Enrollment: 179 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Study group of gynecologic cancer survivors and BMT/SMT cancer survivors:

• History of a primary diagnosis of gynecologic cancer or history of any primary malignancy treated with BMT/SCT
• No evidence of disease for at least one year
• At least 18 years of age not greater than 49 years of age at time of study recruitment
• No other cancer history
• Have impaired fertility: lack of uterus but intact ovaries or lack of ovaries or lack of ovarian function based on the FSH determination but intact uterus
• Have not started or have not completed childbearing
• Able and willing to provide informed consent
• Ability to comprehend and complete questionnaire in English

Comparison Group of non-cancer infertile women awaiting egg (oocyte) donation:

• No cancer history
• At least 18 years of age not greater than 49 years of age at time of study recruitment
• In ovarian failure and on a waiting list for egg (oocyte) donation
• Have not started or have not completed childbearing
• Able and willing to provide informed consent
• Ability to comprehend and complete questionnaire in English

Exclusion criteria

• Inability to participate in an informed consent process
• Patients with a psychiatric disorder precluding response to the survey

Trial design

179 participants in 3 patient groups

1

Description:

gynecologic cancer survivors

Treatment:

Behavioral: survey instrument

2

Description:

survivors of any type of malignancy with history of BMT/SCT

Treatment:

Behavioral: survey instrument

3

Description:

non-cancer infertile women awaiting third party reproduction

Treatment:

Behavioral: survey instrument