Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation (PrevAsPI-Obs)

Centre Hospitalier Universitaire, Amiens

Status: Unknown

Conditions: Risk Factor; Inhalation Pneumonia

Treatments: Other: Risk factors and incidence of IP after inhalation

Study type: Observational

Funder types: Other

Identifiers

NCT03108430

RNI2016-10

Details and patient eligibility

About

Inhalation pneumonia (PI) is common in clinical practice but is rarely studied. For example, there are no data on the incidence of pneumonia after inhalation and risk factors or protective factors to develop one since it is known that anyone who inhaled does not necessarily develop an IP. There is no data on the benefit of treating inhalation by antibiotic therapy pre-emptively although this practice is common. In this context, this observational study wishes to take stock of the situation on the subject in order to determine what actions to implement to prevent IP.

Enrollment: 60 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• In intensive care: Any intubated patient who presented:
• It is a coma with GCS ≤ 12 without VAS protection, whatever the duration
• Either a proven inhalation, defined by the presence in the VAS of gastric fluid or food
• Either a suspected inhalation, defined by the extrahospital anamnesis
• In medicine :
• Any wrong way (defined by a reflex cough when taking food)
• Coma without intubation, regardless of duration or depth

Exclusion criteria

• Patients with VAP

Trial design

60 participants in 3 patient groups

Inhalation pneumonia

Treatment:

Other: Risk factors and incidence of IP after inhalation

Proven inhalations

Treatment:

Other: Risk factors and incidence of IP after inhalation

Suspected inhalations (coma + anamnesis)

Treatment:

Other: Risk factors and incidence of IP after inhalation