Study of Segmental Renal Artery Clamping During Laparoscopic Partial Nephrectomy

Nanjing Medical University

Status: Unknown

Conditions: Kidney Neoplasms; Renal Cell Carcinoma

Treatments: Procedure: Main renal artery clamping; Procedure: Segmental artery clamping

Study type: Interventional

Funder types: Other

Identifiers

NCT01892059

ChiCTR-TRC-13003054

Details and patient eligibility

About

The purpose of this study is to compare the efficacy and safety of the segmental artery clamping and main renal artery clamping during laparoscopic partial nephrectomy

Full description

Renal tumor patients,for whom laparoscopic partial nephrectomy is suitable, will be randomly divided into two groups,segmental artery clamping group and main artery clamping group. All procedures were performed by the same laparoscopic surgeon. Blood loss, operation time, warm ischemia time, complications and affected renal function before and after operation will be recorded and compared. The safety and efficiency of laparoscopic partial nephrectomy with segmental renal artery clamping will be evaluated in comparison with the conventional main renal artery clamping technique.

Enrollment: 100 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 20<age<70yr
• Stage T1a
• Patients volunteered for this study and provided written informed consent

Exclusion criteria

• Bilateral renal tumor
• tumor of solitary kidney
• glomerulonephritis
• renal insufficiency
• GFR of invalid kidney less than 30ml/min
• presence of suspect metastasis
• serious systematic disease: severe coagulation disorders
• important organ insufficiency and severe psychological disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 2 patient groups

Segmental artery clamping

Experimental group

Description:

Patients with Renal tumor are randomized into this group,they will received laparoscopic partial nephrectomy. During operation, the technique of segmental renal artery clamping will performed.

Treatment:

Procedure: Segmental artery clamping

Main renal artery clamping

Active Comparator group

Description:

Patients with renal tumor are randomized into this group,they will received laparoscopic partial nephrectomy. During operation, the technique of traditional main renal artery clamping will be performed.

Treatment:

Procedure: Main renal artery clamping