Study of Skin Parameters in the PROOF Cohort (PEAU PROOF)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Skin Aging

Treatments: Other: Biopsy; Other: Confocal microscopy in vivo; Other: Dermatological clinical examination

Study type: Observational

Funder types: Other

Identifiers

NCT02104960

2013-A00094-41 (Other Identifier)

1308003

Details and patient eligibility

About

This study aims to evaluate skin aging of an homogeneous population of 77 years old patient selected among the PROOF cohort who has been continuously investigated by cardiological examination.

Skin aging will be explored by macroscopic and microscopic evaluation. In particular, skin aging will be measured by an index of clinical aging (SCINEXA) and other complementary measures such as facial photos, standard and High Definition dermoscopy, elastography, sebumetry, in vivo and ex vivo confocal microscopy, and classical histological examinations.

Enrollment: 209 patients

Sex: All

Ages: 75 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• included in the PROOF cohort
• Form consent signed

Exclusion criteria

• Past history of surgery and / or treatment of aesthetic medicine
• neurological disorders
• insulin-dependent diabetes,
• corticosteroids or retinoids (isotretinoin, ...) > 1 year

Trial design

209 participants in 1 patient group

PROOF

Description:

Healthy inhabitants of the city of Saint-Etienne, France, and aged 65 years at the inclusion date. (NCT00759304)

Treatment:

Other: Confocal microscopy in vivo

Other: Biopsy

Other: Dermatological clinical examination