Study of Sonographic Efficacy of Rituximab in Rheumatoid Arthritis (SEWORRA)

University Hospital, Rouen

Status and phase: Completed; Phase 4

Conditions: Rheumatoid Arthritis

Treatments: Drug: Rituximab; Device: ESAOTE MyLab60

Study type: Interventional

Funder types: Other

Identifiers

NCT01765374

2010/081/HP

Details and patient eligibility

About

To detect by sonography relapse of disease activity prior to clinical symptoms in RA patients treated by rituximab.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• failure to at least one TNF-blocking agent

Exclusion criteria

• pregnant or childbearing woman
• Rituximab contraindication
• woman unable to use contraceptive means

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

rituximab

Experimental group

Description:

Only one arm; all patients are treated by rituximab (monotherapy or in combination with conventional DMARD)

Treatment:

Drug: Rituximab

Device: ESAOTE MyLab60