Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular (DOM)

University Hospital, Lille

Status: Completed

Conditions: Dysphagia; Dysarthria; Dysphonia; Dystonia, Primary

Study type: Observational

Funder types: Other

Identifiers

NCT03380676

2013_34

2013-A01299-36 (Other Identifier)

Details and patient eligibility

About

To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement disorders department for idiopathic oromandibular dystonia and matched, healthy control subjects. Voice and speech disorders had to be assessed with the phonetic analysis, perceptive analysis and motor examination modules of the "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria), the Grade, Rough, Breathy, Asthenic, Strained scale, and a computer recording. Activities of daily living had to be assessed with the Oromandibular Dystonia Questionnaire, the Voice Handicap Index and the Deglutition Handicap Index.

Enrollment: 28 patients

Sex: All

Ages: 8+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Both groups: Man or woman Age > 18 years French social security French speaking: fluent
• Oromandibular dystonia group: Idiopathic oromandibular dystonia (focal or associated to other dystonic symptoms)
• Healthy controls group: Same age +/- 2 years than a patient from the oromandibular dystonia group Normal clinical examination

Exclusion criteria

• Both groups: Any pathology making the orthophonic evaluation difficult Property protection regime Deprivation of liberty -Oromandibular dystonia group: Abnormal neurological examination, except dystonic features
• Healthy controls group: History of brain lesion Abnormal neurological examination Swallowing difficulties

Trial design

28 participants in 2 patient groups

Oromandibular dystonia group

Description:

Patients with idiopathic oromandibular dystonia, either focal or associated to other dystonic features including generalized dystonia

Healthy subjects

Description:

Healthy subjects (normal neurological examination), each being age-matched to a subjet of the oromandibular dystonia group