Study of Speech Function in Epileptic Patients Based on Stereoelectroencephalography Signal

Zhejiang University

Status: Active, not recruiting

Conditions: Epilepsy

Treatments: Behavioral: Speech; Device: Stereoelectroencephalography

Study type: Interventional

Funder types: Other

Identifiers

NCT05776745

2022-0113

Details and patient eligibility

About

Based on stereoelectroencephalography model in the treatment of epilepsy patients, this study conducted language-related experimental studies without interfering with normal monitoring treatment. Meanwhile, voice data and intracranial electrophysiological data were collected for analysis. To study the mechanism related to the language function of patients, try to establish a model to decode the intracranial electrophysiological data related to language.

Enrollment: 5 patients

Sex: All

Ages: 16 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with focal refractory epilepsy also need preoperative evaluation with SEEG

Exclusion criteria

• History of major depression or psychiatric disorders and medication that causes symptoms of psychiatric disorders
• Patients with severe cognitive impairment (MMSE score ≤15), unable to complete the language function test

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

Epileptic

Experimental group

Description:

Epileptic with stereoelectroencephalography

Treatment:

Behavioral: Speech

Device: Stereoelectroencephalography