Study of Tai Chi Exercise and Balance in Persons With Parkinson's Disease

Oregon Research Institute

Status and phase

Completed

Phase 2

Conditions

Parkinson's Disease

Treatments

Behavioral: Tai Chi

Behavioral: Strength training

Behavioral: Low-Impact Exercise Control

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT00611481

R01NS047130 (U.S. NIH Grant/Contract)

NS047130

Details and patient eligibility

About

Patients practicing Tai Chi will exhibit significant improvements in primary outcome measures of balance, and secondary outcomes of gait, physical performance, Unified Parkinson's Disease Rating Scale, Falls, muscle strength.

Full description

The study is designed to determine the effects of Tai Chi training on balance and other functional outcomes in persons with Parkinson's disease.

Enrollment

195 patients

Sex

All

Ages

40 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients who have:

A diagnosis of idiopathic PD, with a disease severity rating of stage I to IV on the Hoehn and Yahr scale (Hoehn & Yahr, 1967)
At least 1 score of 2 or more for at least 1 limb for either the tremor, rigidity, or bradykinesia item of the Unified Parkinson's Disease Rating Scale (UPDRS)
Stable medication usage
Not participated in a structured exercise program (i.e., not involved in any routine, organized physical activity program lasting 30 minutes or more per day, such as a gym program or regularly scheduled instructor-led exercise class) in the previous 2 months
Ability to stand unaided or walk independently; had a personal physician's or neurologist's clearance for participation; and had a willingness to be assigned to intervention conditions.

Exclusion criteria

Patients who:

Participate in any other behavioral or pharmacological research study
Have cognitive decline (Mini-Mental State Examination score, ≤ 24) (Folstein et al., 1975)
Have self-reported diagnosis of Alzheimer disease or other severe neurological (stage III and IV PD)
Have evidence of progressive or debilitating conditions (metastatic cancer, severe heart or lung disease, crippling arthritis) or severe losses in vision and hearing that would limit their tolerance to testing and training procedures, that would interfere with study participation
Are unavailable during the study period.