Study of the Colonic Carriage of Staphylococcus Aureus in a Prospective Cohort of Patients Undergoing Endoscopic Screening for Digestive Cancer in the University Hospital of Saint-Etienne (ColoStaph)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: STAPHYLOCOCCAL INFECTIONS

Treatments: Other: Staphylococcus aureus carriage

Study type: Interventional

Funder types: Other

Identifiers

NCT02502474

2014-A00755-42 (Other Identifier)

1408023

Details and patient eligibility

About

Epidemiological study aiming to describe the carriage (nasal, throat, groin, rectal and colonic) of S. aureus in patients without chronic digestive disease who are going to have a colonoscopy for cancer screening. The carriage will be analyzed globally and the similarity of strains isolated from each site will be analyzed using molecular tools. The aim of this study is to better estimate the digestive reservoir of S. aureus to better prevent endogenous infections due to this bacterium.

Enrollment: 112 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient affiliated to French social security
• Written consent of the patient
• Patient needing a colonoscopy in the University Hospital of Saint-Etienne, France

Exclusion criteria

• Patient who decline to participate to the study
• Patient in the incapacity to give consent
• Patient receiving treatment with anticoagulant or antiaggregant platelets
• Patients with a known haemostatic disorder
• Pregnant woman
• Patients with a chronic disease of the gastrointestinal tract
• Patients receiving long-term corticosteroid
• Patient receiving anti staphylococcal antibiotics

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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112 participants in 1 patient group

Patients undergoing a colonoscopy

Experimental group

Description:

Staphylococcus aureus carriage is measured in nose, throat, colon, rectum and groin

Treatment:

Other: Staphylococcus aureus carriage