Study of the Correlation Between UltraSonography and Dual-Energy Computed Tomography Assessment of Urate Deposit (GOUT)

Lille Catholic University

Status: Completed

Conditions: Gout

Treatments: Procedure: DECT; Procedure: ultrasonography

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03162341

RC-P0056

Details and patient eligibility

About

The objective of this research is to evaluate the correlation between DECT and US explorations performed in a routine clinical setting for the measurement of change in tophus size in gout patients after 24 months of treatment.

Enrollment: 60 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of gout based on the ACR/EULAR 2015 criteria
• uricemia ≥6 mg/dL
• warranted introduction of urate-lowering therapy according to the ACR 2012 or EULAR 2016 criteria
• signature of the informed consent
• social insurance affiliation

Exclusion criteria

• pregnancy or breastfeeding
• patient under legal guardianship

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

UltraSonography and DECT

Experimental group

Description:

UltraSonography and DECT will be used in patient monitoring after 6, 12 and 24 months of treatment in order to evaluate the correlation between the 2 explorations for the measurement in tophus volume change. Those are interventions that are not part of the standard care of the patients.

Treatment:

Procedure: ultrasonography

Procedure: DECT