Study of the Effect of General Anesthesia on Children's Behavior

Shanghai Jiao Tong University

Status: Unknown

Conditions: Behavior

Treatments: Other: Achenbach Child Behavior Checklist （CBCL）scale

Study type: Observational

Funder types: Other

Identifiers

NCT05164913

SH9H-2019-T12

Details and patient eligibility

About

This topic speculates that there is an interaction between family environment and anesthetic drug exposure on children's behavior. Different family environments have different response to anesthetic drug exposure. Children living in a specific family environment may be more susceptible to the effects of anesthetic drugs. People who are susceptible to exposure to narcotic drugs. In order to clarify this hypothesis and discover specific family environment factors that interact with anesthetic drug exposure, this project intends to establish a retrospective cohort study, through hierarchical analysis and other means, to clarify the behavioral changes of children in different family environments after exposure to anesthetic drugs. Provide theoretical support for the safe application of clinical children's anesthetics.

Enrollment: 1,140 estimated patients

Sex: All

Ages: 5 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 0-5 who underwent surgery at Shanghai Ninth People's Hospital
• Current age is less than 18 years old
• No surgical complications such as acute infectious diseases, systemic diseases

Exclusion criteria

• History of neonatal hypoxic ischemic encephalopathy and bilirubin encephalopathy
• There are genetic diseases or chromosomal diseases, neurological diseases (including epilepsy, congenital diseases), or a history of head trauma, a history of central nervous system infectious diseases, high fever convulsions, congenital heart disease, tumor diseases, and Patients with blood diseases
• People who have autism, attention deficit hyperactivity disorder, or have received behavioral related treatments and interventions
• Those who have undergone cardiovascular surgery, neurosurgery, or those with unstable hemodynamics during surgery
• Those who cannot be contacted, refused to join the group, the questionnaire information does not match the medical records, or the complete medical records cannot be obtained

Trial design

1,140 participants in 3 patient groups

Control group

Description:

No general anesthesia between 0-3 years old or 0-5 years old

Treatment:

Other: Achenbach Child Behavior Checklist （CBCL）scale

Single anesthesia group

Description:

Only once general anesthesia between 0-3 years old or 0-5 years old

Treatment:

Other: Achenbach Child Behavior Checklist （CBCL）scale

Multiple anesthesia group

Description:

More than once general anesthesia between 0-3 years old or 0-5 years old

Treatment:

Other: Achenbach Child Behavior Checklist （CBCL）scale