Study of the Effects of Chemotherapy on Memory and Other Mental Functions in Women With Breast Cancer

Ottawa Hospital Research Institute

Status: Completed

Conditions: Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT00260975

1999232-01H

Details and patient eligibility

About

Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog. The current study is investigating this phenomenon by measuring mental function of breast cancer patients prior to and after exposure to chemotherapy, and by comparing mental function in those patients who receive chemotherapy and those who do not.

Full description

Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog. The current study will investigate this phenomenon by measuring neuropsychological functioning in early stage breast cancer patients prior to and after exposure to chemotherapy, and by comparing change in cognitive function in patients who receive chemotherapy to similar breast cancer patients receiving hormonal therapy only.

Enrollment: 112 patients

Sex: Female

Ages: 50 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• stage I or II breast cancer; woman; 50-65 years old; post-menopausal

Exclusion criteria

• history of previous cancer or chemotherapy; significant neurological or psychiatric history

Trial design

112 participants in 2 patient groups

Chemotherapy patients

Description:

Breast cancer patients treated with adjuvant chemotherapy of various types.

Hormonal patients

Description:

Breast cancer patients treated with adjuvant hormonal therapy but not chemotherapy.