Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease
Status and phase
Conditions
Treatments
Details and patient eligibility
About
Alzheimer's disease is a medical illness that damages the brain and causes problems with memory, mood and behavior. A substance called acetylcholine (ACh), which is naturally produced in the body, plays an important role in the normal functioning of the brain. In subjects with Alzheimer's disease, the level of ACh is greatly reduced. Currently, there are three commonly prescribed drugs used for treating the symptoms of Alzheimer's disease by helping to maintain the level of ACh in the brain. This study will evaluate how much each of these drugs changes the levels of certain brain chemicals that are known to, or may play an important role in, Alzheimer's disease and its symptoms.
Sex
Ages
Volunteers
Inclusion criteria
- Clinical diagnosis of mild to moderate Alzheimer's disease
- Must be able to swallow capsule/tablet
- Must have a caregiver who is available to attend all study visits
Exclusion criteria
- Digestive problems related to peptic ulcer
- Experienced a heart attack or stroke in the last 6 months
- Serious/unstable asthma or severe pulmonary (lung) disease
- On current treatment with a blood thinner
Trial design
Primary purpose
Allocation
Interventional model
Masking
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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