Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone

David Weinstein

Status: Terminated

Conditions: Cutaneous Lupus

Treatments: Device: 1064nm laser; Device: 532nm laser; Drug: Topical corticosteroid

Study type: Interventional

Funder types: Other

Identifiers

NCT03639857

BIO-17-13680

Details and patient eligibility

About

This study aims to compare the efficacy of 532nm Potassium Titanyl Phosphate (KTP) laser and 1064 nm Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) laser as adjuncts to topical corticosteroids in the treatment of cutaneous lupus erythematosus versus topical corticosteroids alone.

Enrollment: 3 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female adult 18 years of age or older
• Ability to rate level of pain
• Ability to rate visual satisfaction
• At least 2 active lesions of CLE

Exclusion criteria

• New or change in systemic medication for cutaneous lupus in past 6 months
• Allergy to triamcinolone or betamethasone dipropionate cream
• Pregnancy
• Currently a prisoner
• Unable to read and speak English since consent will only be available in English

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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3 participants in 3 patient groups

532nm laser and topical corticosteroid

Experimental group

Description:

532nm laser is applied to the patient's lesion in-clinic in addition to a topical corticosteroid.

Treatment:

Drug: Topical corticosteroid

Device: 532nm laser

1064nm laser and topical corticosteroid

Experimental group

Description:

1064nm laser is applied to the patient's lesion in-clinic in addition to a topical corticosteroid.

Treatment:

Drug: Topical corticosteroid

Device: 1064nm laser

Topical corticosteroid alone

Active Comparator group

Description:

Topical corticosteroid is applied to the patient's lesion.

Treatment:

Drug: Topical corticosteroid