Study of the Efficience of Chewing-gum to Reduce the Duration of Postoperative Ileus (CHEWIP)

University Hospital, Angers

Status: Completed

Conditions: Postoperative Ileus

Treatments: Behavioral: chewing

Study type: Interventional

Funder types: Other

Identifiers

NCT05296967

2021_A03140_41

Details and patient eligibility

About

Postoperative ileus (POI) is a serious complication after surgery. While it complicates all type of surgery, it is more frequent after abdominal surgery (especially bowel or colorectal surgery).

Many studies aim to reduce the occurence of POI without efficiency. The aim of this study is to assess the efficiency of the vagal stimulation, by the mean of chewing, to reduce the duration of POI.

Enrollment: 128 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients undergoing colorectal surgery or small bowel surgery
• elective or in emergency
• open surgery or laparoscopy
• diagnosis of POI
• indication of fasting or nasogastric tube placement

Exclusion criteria

• contra-indication of chewing
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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128 participants in 2 patient groups

Chewing gum

Experimental group

Description:

POI patients are asked to chew 20 minutes x2/ day

Treatment:

Behavioral: chewing

No chewing

No Intervention group

Description:

POI patients receive no intervention