Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation (DOP-RENAL)

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Acute Renal Failure

Study type: Observational

Funder types: Other

Identifiers

NCT04682236

8059

Details and patient eligibility

About

Liver transplantation is associated with a modification of the perfusion pressures of the abdominal organs (preoperative portal hypertension in connection with liver pathology, and normalization of the perfusion pressures during surgery). This abrupt change in the infusion regime is probably responsible for an alteration in renal function in some patients, and the identification of renal vascular profiles using Doppler could point to pathological profiles, which should be diagnosed early.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient of full age (≥18 years)
• Patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30, 2020.
• Patients having undergone an evaluation of hepatic and renal vascular profiles perioperatively.
• Patients hospitalized in the surgical intensive care unit after hepatic transplant surgery.
• Patient not having expressed, after information, the reuse of his data for the purposes of this research

Exclusion criteria

• Patient who expressed his opposition to participating in the study
• Patient with suspected obstructive acute renal failure
• Stenosis of renal arteries known at the time
• End-stage renal disease on dialysis
• Impossibility of giving the subject informed information (difficulties in understanding the subject, etc.)
• Subject under safeguard of justice