Study of the Influence of the Expression of the Calcium-sensitive Receptor (CaSR) by Monocytes in the Synovial Liquid on Structural Alterations in Patients Diagnosed With Rheumatoid Arthritis in the Previous Two Years (CASPER)

Centre Hospitalier Universitaire, Amiens

Status: Completed

Conditions: Arthritis, Rheumatoid

Treatments: Biological: blood

Study type: Observational

Funder types: Other

Identifiers

NCT02894047

PI2013_843_0014

Details and patient eligibility

About

Rheumatoid arthritis (RA) is the most frequent form of chronic inflammatory rheumatism in adults. The erosive damage influences the functional prognosis in patients with RA. At present, there are no sufficiently sensitive and specific predictive markers of erosive damage.

Enrollment: 42 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients consulting in the Department of Rheumatology at Amiens University Hospital
• Age ≥ 18
• RA meeting the 2010 ACR/EULAR criteria
• Less than 2 years of RA progression
• Effusion in at least 1 joint

Exclusion criteria

• Inability to give informed consent
• Ongoing pregnancy
• Previous treatment with an anti-osteoporosis medication
• Intra-articular corticoid or hyaluronic acid injection in the previous 6 months
• Coagulation disorders preventing arthrocentesis
• Incarceration or legal guardianship