Study of the Preservation of the Left Colic Artery on Rectum Cancer Surgery (POTLCAORCS)

Jian Suo

Status: Completed

Conditions: Rectum Cancer

Treatments: Procedure: not preserving the left colic artery; Procedure: preserving the left colic artery

Study type: Interventional

Funder types: Other

Identifiers

NCT01979029

Left Colic Artery

Details and patient eligibility

About

To evaluate the influence to the blood supply of the anastomosis and the harvest of the No. 253 lymph nodes in different surgical methods--- preserving the left colic artery (LCA) and resect the No. 253 lymph node specifically in the radical resection of rectal carcinoma or dividing at the root of the inferior mesenteric artery (IMA) in the radical resection of rectal carcinoma.

Full description

Methods: The patients who got rectal carcinoma are divided into two groups. Both groups will receive the radical resection of rectal carcinoma. We preserve the left colic artery and resect the No. 253 lymph node specifically in Group A and divide at the root of the inferior mesenteric artery in Group B, We insert a trocar into the arterial arcade at the proximal site of the anastomosis and measure the blood pressure of the arterial arcade in the operation, which can reflect the blood supply of the anastomosis. Besides, We will measure the length of the colon from the anastomosis to the level of the root of the IMA. Expecting Results：The blood pressure of the arterial arcade in Group A will be higher than that in Group B. And the patients in Group A will have less chance to get anastomotic fistula. Expecting Conclusions: Preserving the LCA and resecting the No. 253 lymph node specifically in the radical resection of rectal carcinoma can improve the blood supply of the anastomosis and decrease the incidence of anastomotic fistula, and won't affect the harvest of the No. 253 lymph node.

Enrollment: 57 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients coming to FirstJilinU diagnosed rectum cancer by endoscopy and pathology.
• The rectum cancer is the first malignant neoplasm the patient has got.
• The cancer is solitary, and is 3cm to 20cm to the anus.
• The surgical method is limited to Dixon.

Exclusion criteria

• Being in the acute phase of inflammation before operation and emergency surgery.
• Patients receiving steroid medication or preoperative radiotherapy。
• Discovering macrometastasis before or in the operation.
• The rectum cancer that can't be radical resected.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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57 participants in 2 patient groups

preserving the left colic artery

Experimental group

Description:

We preserve the left colic artery and resect the No. 253 lymph node during the rectal surgery.

Treatment:

Procedure: preserving the left colic artery

not preserving the left colic artery

Experimental group

Description:

We preserve the high ligation of the inferior mesenteric artery during the rectal surgery.

Treatment:

Procedure: not preserving the left colic artery