Study of the Prevalence of Autistic Traits in Angelman Syndrome

IRCCS Eugenio Medea

Status

Enrolling

Conditions

Angelman Syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT06337383

12.2021 ANGELMAN

Details and patient eligibility

About

The goal of this observational cross-sectional study is to establish the prevalence of autism spectrum disorder in children and adolescents with Angelman syndrome. The main questions it aims to answer are:

which clinical variables differentiate AS patients with and without Autism Spectrum Disorder between genetics, epilepsy, pharmacotherapy, behavioural problems, parenting style and parents' perceived stress.
which clinical variables differentiate parenting styles and levels of perceived stress.

Data from neuropsychological, speech therapy and physiotherapeutic assessments are collected during regular clinical follow-ups, regarding: cognitive development ("Bayely Scales of Infant Development-III", Cognitive Scale) and adaptive behaviour; Autism and Autism Spectrum Disorder ("Autism Diagnostic Observational Schedule-2"); parental stress and parenting styles; social-communicative skills; motor development.

Enrollment

46 estimated patients

Sex

All

Ages

4 to 14 years old

Volunteers

No Healthy Volunteers

Inclusion criteria