Study of the Prevalence of Endometriosis and Adenomyosis (PrevADEOSE)

Assistance Publique - Hôpitaux de Paris

Status

Enrolling

Conditions

Elective Fertility Preservation

Treatments

Other: Usual follow-up

Study type

Observational

Funder types

Other

Identifiers

NCT06211569

2023-A01474-41 (Other Identifier)

APHP231461

Details and patient eligibility

About

Our study aims to assess the prevalence of adenomyosis and endometriosis in patients consulting for elective fertility preservation through the diagnosis of these pathologies by transvaginal pelvic ultrasound. Imaging data will be compared with clinical data (patient characteristics, clinical symptoms) as well as the assessment of anxiety, depression, and quality of life collected from the women.

Full description

Adenomyosis and endometriosis are two heterogeneous benign gynecological pathologies, in terms of the presence of diverse phenotypes and their symptomatic presentation: While some women are entirely asymptomatic, others experience pelvic pain, infertility, or abnormal uterine bleeding.

Assessing the prevalence of these two pathologies is challenging: On the one hand, a significant number of women are asymptomatic and not considered in the calculation; on the other hand, endometriosis and adenomyosis are often underdiagnosed, leading to delayed diagnosis.

Endometriosis and adenomyosis are frequently associated. Improving knowledge about the epidemiology of endometriosis and adenomyosis is crucial as both are major causes of clinical symptoms that adversely affect the quality of life in numerous women. This is a significant issue for women's health due to the associated suffering, numerous surgical interventions, healthcare expenses, and the suggested link with pathologies that may affect other organs. Understanding the disease could lead to improved treatment and the development of preventive strategies.

Therefore, it is urgent to determine the frequency of endometriosis and adenomyosis, as well as the correlation between women's characteristics, especially their clinical symptoms, and different phenotypes. In order to assess the prevalence of adenomyosis and endometriosis in a population of women of reproductive age, the investigators intend to conduct this single-center study focusing on patients consulting for non-medical fertility preservation.

Enrollment

400 estimated patients

Sex

Female

Ages

29 to 37 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Woman aged between 29 and 37
Consultant for non-medical fertility preservation in the Reproductive Medicine Unit Port Royal, Cochin
Informed and not opposed to this research
Affiliated to a social security scheme

Exclusion criteria