Study of the Relationship Between Blood Groups,RH and Skeletal Malocclusion : a Cross Sectional Study

Cairo University (CU)

Status: Unknown

Conditions: Class III Malocclusion; Class II Malocclusion

Treatments: Diagnostic Test: blood type test

Study type: Observational

Funder types: Other

Identifiers

NCT03085082

skeletal_malocclusion_ABO

Details and patient eligibility

About

the study is searching if there is a relationship between the blood groups and RH and the skeletal malocclusion using the skeletal class I as a control group

Full description

The study will be conducted on the patients seeking medical care in the orthodontic department Cairo University, for six months all patients with class II and class III malocclusion will be recruited based on Wits appraisal measured from the cephalometric X-ray taken routinely during orthodontic examination. Then a group of class I arch length discrepancy patients will be used as control. A blood sample will be withdrawn and taken to the Cairo university laboratory to analyze the blood group and RH .a statistical analysis will be performed to detect a relationship between skeletal malocclusion and the blood groups as compared to the control

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

skeletal class I,II and III patients non syndromic patients above the age of 18 no previous surgical intervention for correction of skeletal malocclusion

Exclusion criteria

• syndromic patients
• cleft patients
• patients with previous surgery to correct skeletal malocclusion

Trial design

300 participants in 3 patient groups

skeletal class II subjects

Description:

patients with wits appraisal more than 3 mm measured on a cephalometric x ray obtained during diagnosis

Treatment:

Diagnostic Test: blood type test

skeletal class III subjects

Description:

patients with wits appraisal less than -3 mm measured on a cephalometric x ray obtained during diagnosis

Treatment:

Diagnostic Test: blood type test

skeletal class I patients

Description:

patients with Wits appraisal between -3 and +3 that is measured from a cephalometric x ray obtained during diagnosis of arch length discrepancy. this group will serve as control and obtained after recruitment of the other 2 groups in 1 to 1 fashion

Treatment:

Diagnostic Test: blood type test