Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) (VISA)

P

Poitiers University Hospital

Status

Completed

Conditions

Vigilance Dysfunction

Treatments

Diagnostic Test: tests of attentional performance

Study type

Interventional

Funder types

Other

Identifiers

NCT03344263
VISA

Details and patient eligibility

About

It is a monocentric prospective pilot study in Poitiers University Hospital, specifically analyzing the vigilance disorders in the Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and their reversibility after 6 months of Continuous positive airways pressure (CPAP). All subjects were administered a test of vigilance (Test of Attentional Performance) both before and after the 6 months of CPAP. The main objective is the study of the reversibility of alertness disorders on the number of omissions in the subtest visual vigilance of the TAP ( (Test of Attentional Performance) at 6 months of CPAP in the OSAHS in patients with a memory complaint.

Enrollment

23 patients

Sex

All

Ages

20 to 69 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients aged 20-70 years
  • Memory disorders without memory problems in episodic memory

Presence of polysomnography of a obstructive sleep apnea/hypopnea syndrome (OSAHS) requiring Continuous positive airways pressure

  • Moderate OSAHS (Apnea Hypopnea Index ≥ 15 / hour with arousals ≥ 10)
  • Severe OSAHS (Apnea Hypopnea Index ≥ 30 / h)

Exclusion criteria

  • Age <20 years or ≥ 70 years
  • Neurodegenerative disease (Alzheimer's disease, Parkinson's disease)
  • Dysthyroidism
  • Severe depression, schizophrenia, bipolar disorder
  • Treatment with an effect on cognition: hypnotics, sedative
  • Chronic Obstructive Pulmonary Disease
  • Chronic alcoholism, other addictions
  • Contraindications to Magnetic Resonance Imaging
  • Refusal of equipment

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

23 participants in 1 patient group

tests of attentional performance
Experimental group
Treatment:
Diagnostic Test: tests of attentional performance

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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