Study of the Treatment of Tendinopathy Unruptured of Rotator Cuff by Intramuscular Injection of Botulinum Toxin (Botox shoulder)

Versailles Hospital

Status and phase

Unknown

Phase 2

Conditions

Tendinopathy Rotator Cuff

Treatments

Drug: Botox arm

Study type

Interventional

Funder types

Other

Identifiers

NCT02867787

P13/09_ Botox

Details and patient eligibility

About

Botulinum toxin is used in musculoskeletal therapy routinely for 15 years. This is one of the most potent neurotoxins. It comes in 7 serotypes (A to G).Therapeutic application of botulinum toxin are mainly based on its ability to block the neuromuscular transmission by preventing the release of acetylcholine, creating paralysis muscle relative and reversible.

It has been used in the treatment of cervical dystonia, migraine headaches, and an antinociceptive effect. The analgesic effect occurred even prior to the release muscular. Several randomized studies have been published about it. The investigators assume that intramuscular injection of botulinum toxin is effective in the treatment of tendinopathy rotator cuff.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Signed consent
Active social care
Compliant patient with protocol
Patient more than 18 years
Positive Neer Test

Exclusion criteria

Prior study exclusion period
Protected patient
Study refusal
Deficient patient
Rheumatoid arthritis, osteoarthritis, chondrocalcinosis.
Microcrystalline arthritis.
Active infection .
History of hypersensitivity reaction during a previous injection of botulinum toxin
Bilateral involvement
Neurological deficit
Depression
History of shoulder surgery
Pregnant or breast feeding women
Systemic disease (diabeta, vascularitis)
Known neurological disease
Intraarticular associate disease
Acromioclavicular associate disease
Myasthenia
Botulinum toxin is not recommended in combination with aminoglycosides