Study of Thyroid Status in Patients With IBD

Assiut University

Status: Not yet enrolling

Conditions: Irritable Bowel Disease; Thyroid Disease

Treatments: Diagnostic Test: Thyroid tests

Study type: Observational

Funder types: Other

Identifiers

NCT05542368

thyroid state in IBD patients

Details and patient eligibility

About

. The aim of the present study is to study thyroid state in patients with IBD

Full description

All patients were subjected to history taking and physical examination with emphasis on history of autoimmune disease, extraintestinal manifestations of IBD, neck examination for goiter, symptoms and signs of thyroid dysfunction.

b) Laboratory investigations: Thyroid function test (include T3-T4- TSH)

• ESR - CRP - thyroid antibodies: (Anti TPO -Anti Thyroglobulin)

  c)-Imaging:

• Neck U/S on thyroid gland to identify patients with ultrasonographic evidence of autoimmune thyroiditis (diffuse hypoechogenicity or heterogenicity echotexture or both) and to detect thyroid nodularity.

d ) Endoscopic findings regarding diagnosis of IBD confirmed by histopathological examination

Enrollment: 90 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: All patients with IBD

Exclusion Criteria:

• patients with
• Thyroid disease
• Acute or chronic kidney
• Acute or Chronic Liver Disease. Active Lupus -
• Malignancy
• patients taking medications that affect thyroid function as rifampin, amiodarone .....

Trial design

90 participants in 2 patient groups

Patients with IBD

Description:

All patients were subjected to history taking and physical examination with emphasis on history of autoimmune disease, extraintestinal manifestations of IBD, neck examination for goiter, symptoms and signs of thyroid dysfunction. b) Laboratory investigations: Thyroid function test (include T3-T4- TSH) * ESR - CRP - thyroid antibodies: (Anti TPO -Anti Thyroglobulin) c)-Imaging: * Neck U/S on thyroid gland to identify patients with ultrasonographic evidence of autoimmune thyroiditis (diffuse hypoechogenicity or heterogenicity echotexture or both) and to detect thyroid nodularity. d ) Endoscopic findings regarding diagnosis of IBD confirmed by histopathological examination

Treatment:

Diagnostic Test: Thyroid tests

Healty individuals as a control group

Description:

All patients were subjected to history taking and physical examination with emphasis on history of autoimmune disease, extraintestinal manifestations of IBD, neck examination for goiter, symptoms and signs of thyroid dysfunction. b) Laboratory investigations: Thyroid function test (include T3-T4- TSH) * ESR - CRP - thyroid antibodies: (Anti TPO -Anti Thyroglobulin) c)-Imaging: * Neck U/S on thyroid gland to identify patients with ultrasonographic evidence of autoimmune thyroiditis (diffuse hypoechogenicity or heterogenicity echotexture or both) and to detect thyroid nodularity.

Treatment:

Diagnostic Test: Thyroid tests