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Study of Tissue Samples From Patients With Glioma or Other Brain Tumors

University Hospital Center (CHU) logo

University Hospital Center (CHU)

Status

Completed

Conditions

Central Nervous System Lymphoma

Treatments

Other: pharmacogenomic studies
Other: laboratory biomarker analysis

Study type

Observational

Funder types

Other

Identifiers

NCT00967200
7745 (Other Identifier)

Details and patient eligibility

About

RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.

Full description

OBJECTIVES:

Primary

  • To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches.

Secondary

  • To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy.

OUTLINE: This is a multicenter study.

Biological samples are collected from patients at time of surgery for diagnostic and/or treatment purposes.

Enrollment

180 patients

Sex

All

Ages

18 to 120 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Histologically confirmed glioma of any grade or rare primary brain tumor No urgent situation No known or suspected active infection Must not be deprived of liberty or protected by law Not pregnant or nursing

Exclusion :

No concurrent participation in other trials that require a period of exclusion

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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