Study of Urinary Impact of Spinal Dysraphism in the Pediatric Population (SPINA)

University Hospital, Angers

Status: Not yet enrolling

Conditions: Closed Dysraphism; Dysraphism; Open Dysraphism

Treatments: Other: description of the impact

Study type: Observational

Funder types: Other

Identifiers

NCT07258654

49RC25_0272

Details and patient eligibility

About

Spinal dysraphisms are defined as a congenital malformation characterized by a defect in the closure of the neural tube in the caudal region. They are divided into two groups: open dysraphisms, where the skin covering is absent; and closed dysraphisms, where the skin abnormality is less obvious and diagnosis is sometimes more difficult. Both open and closed dysraphisms can cause a variety of neurological disorders, including urinary and fecal dysfunction, which is often more severe in open dysraphisms than in closed dysraphisms, which sometimes go unnoticed and may only become symptomatic during growth. As a result, urinary and fecal repercussions in closed dysraphisms are sometimes overlooked, and the literature on this subject remains scarce. The hypothesis is that a better understanding of the urinary and fecal repercussions of closed dysraphisms would allow for more appropriate and standardized follow-up of these children. The main objective of the study is to describe the urinary impact on children with spinal dysraphism, as well as how they are managed.

Enrollment: 210 estimated patients

Sex: All

Ages: Under 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• treated or cared for at Angers University Hospital for spinal dysraphism between January 1, 2014, and December 31, 2024

Exclusion criteria

• Differential diagnosis of dysraphism

Trial design

210 participants in 1 patient group

Dyspraphism

Treatment:

Other: description of the impact