Study of Yoga as a Therapy for Cystic Fibrosis (CF) Patients
Status
Conditions
Treatments
Details and patient eligibility
About
Cystic fibrosis (CF) is a lung disease that affects 30,000 children and adults in the US. Incorporation of regular exercise into the lives of patients with CF is of interest because it may improve lung function and quality of life. Yoga is an activity that may benefit patients with CF in many ways including strengthening muscles of breathing, improving lung function, and reducing stress which could improve quality of life and adherence to therapies. Yoga has been shown to be beneficial in patients with other lung diseases such as asthma, but has not yet been studied in CF.
The investigators hypothesize that yoga will be an activity that is safe and tolerable for CF patients 12 to 25 years of age. The primary aim is to investigate the safety and tolerability of an 8 week yoga program for patients with CF. The secondary aim is to determine the effect of yoga on many aspects of CF disease including respiratory symptoms, adherence to regular CF therapies, quality of life, lung function, exercise tolerance, and nutritional status.
The long-term goal is to use the data obtained in this study to design a future study of the efficacy of yoga in a larger population of CF patients at multiple CF centers. This research has the potential to influence the prevention and treatment of CF by providing data which could be used to help understand the most appropriate and beneficial type of physical activity for CF patients.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
o Diagnosis of CF by: Sweat chloride ≥60meq/L on two occasions or CFTR genotype with two CF disease-causing mutations and one or more phenotypic features of CF
- Age ≥12 and ≤25 years
- FEV1 ≥40 % predicted at screening visit
- Informed consent and assent
Exclusion criteria
- Wheezing on auscultation of the chest at the enrollment visit
- Oxygen saturation < 90 % at the enrollment visit
- Initiation of treatment with oral, inhaled or intravenous antibiotics for an acute respiratory infection in the 2 weeks preceding the enrollment visit
- Pregnancy
- History of lung transplant
- Practiced yoga regularly (≥1 time per week) in the month prior to enrollment
- Current enrollment in a therapeutic clinical trial
- Condition or situation which, in the opinion of the investigator, would affect the ability of the patient or family to complete study procedures
Trial design
20 participants in 2 patient groups
Trial contacts and locations
Loading...
Central trial contact
Sharon McNamara
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal