Study on Abnormal Dopamine Synthesis and Connectivity According to the Antipsychotic Treatment Response in Schizophrenia

Seoul National University

Status: Completed

Conditions: Schizophrenia

Treatments: Other: patients treated with antipsychotics

Study type: Observational

Funder types: Other

Identifiers

NCT02248987

3420130030

Details and patient eligibility

About

The purpose of this study is to evaluate abnormal dopamine synthesis and connectivity according to the antipsychotic treatment response in schizophrenia.

Enrollment: 36 patients

Sex: All

Ages: 20 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosis of schizophrenia
• clinically stable state

Exclusion criteria

• history of previous head injury, epileptic disorder, other medical comorbidity
• substance abuse/dependence

Trial design

36 participants in 3 patient groups

Clozapine

Description:

stable patients treated with clozapine

Treatment:

Other: patients treated with antipsychotics

Other antipsychotics

Description:

stable patients treated with risperidone or paliperidone or olanzapine

Treatment:

Other: patients treated with antipsychotics

Healthy volunteer

Description:

healthy controls

Treatment:

Other: patients treated with antipsychotics