Study on Communication Comprehension in the Schizophrenic Spectrum (SKYPROVERB)

Hôpital NOVO

Status: Completed

Conditions: Schizophrenia Simple

Treatments: Behavioral: Emotional judgment task; Behavioral: Detection task; Other: CAPE-42; Diagnostic Test: Positive And Negative Syndrome Scale; Diagnostic Test: Trait Emotional Intelligence Questionnaire; Behavioral: Recognition task; Other: Mini International Neuropsychiatric Interview; Behavioral: Post-experimental questionnaire

Study type: Interventional

Funder types: Other

Identifiers

NCT03225027

CHRD0814

Details and patient eligibility

About

The purpose of the present study is to evaluate the effect of emotional prosody on the perception of emotional discourse in the schizophrenic spectrum. The investigators hypothesize that participant may use emotional prosody as an emotional cue to understand the emotional content of discourse.

Full description

The integration of ortholinguistic and paralinguistic functions in language, particularly of the emotional prosody, is necessary to interact adaptively with others. People in the schizophrenic spectrum have social difficulties. Is emotional prosody comprehension altered in these people? According to Edwards et al. (2002), there is methodological issues concerning the tasks used to answer this question. Investigators built an emotional judgment task more adapted to study the perception of emotional prosody in the schizophrenic spectrum than the classical paradigm designed to evaluate participants with cerebral injury. The investigators have elaborated a material that consists of 140 short sentences (7±2 words) with a simple syntactic structure. The verbal content expressed positive, neutral or negative emotions. These sentences were announced by four professional actors (two female) with an emotional prosody content congruent or inconsistent with the verbal content. Participants will have to evaluate the emotional intensity of the recordings on a five points Likert scale, from strongly negative to strongly positive. Psychotic experiences of all participants will be evaluated too.

Enrollment: 59 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Having a diagnosis of schizophrenia and being in a stable phase of the disease
• Having between 18 to 60 years old
• Speak french or using french at school
• Accepting not to use psychoactive substances during the preceding 48h
• Being affiliated to the French social security
• Providing their written informed consent

Non-inclusion Criteria:

• Having not audio deficits, nor visual uncorrected deficits
• Having not suffering from depressive symptoms during the last 6 months

Exclusion criteria

• Having no neurological, nor psychiatric disease except schizophrenia for the patients groups.

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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59 participants in 3 patient groups

Patients with schizophrenia

Experimental group

Description:

Emotional judgment task, post-experimental questionnaire, recognition task, detection task, questionnaire CAPE-42, trait emotional intelligence questionnaire and positive and negative syndrome scale.

Treatment:

Behavioral: Detection task

Behavioral: Recognition task

Behavioral: Emotional judgment task

Other: CAPE-42

Diagnostic Test: Trait Emotional Intelligence Questionnaire

Diagnostic Test: Positive And Negative Syndrome Scale

Behavioral: Post-experimental questionnaire

Few psychotic experiences

Experimental group

Description:

Healthy participants with few psychotic experience. Participants with the lowest score to the CAPE-42 test. Mini International Neuropsychiatric Interview

Treatment:

Behavioral: Detection task

Behavioral: Recognition task

Behavioral: Emotional judgment task

Other: CAPE-42

Other: Mini International Neuropsychiatric Interview

Diagnostic Test: Trait Emotional Intelligence Questionnaire

Behavioral: Post-experimental questionnaire

Several psychotic experiences

Experimental group

Description:

Healthy participants with several psychotic experiences. Participants with the highest score to the CAPE-42 test. Mini International Neuropsychiatric Interview

Treatment:

Behavioral: Detection task

Behavioral: Recognition task

Behavioral: Emotional judgment task

Other: CAPE-42

Other: Mini International Neuropsychiatric Interview

Diagnostic Test: Trait Emotional Intelligence Questionnaire

Behavioral: Post-experimental questionnaire