Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease

Peking University

Status

Completed

Conditions

Dry Eye

Treatments

Other: acupuncture

Drug: Sodium hyaluronate eye drops

Study type

Interventional

Funder types

Other

Identifiers

NCT04668131

20200922

Details and patient eligibility

About

This project is designed as a prospective, randomized, open, controlled clinical trial. For the first time, acupuncture was applied to the treatment of dry ocular neuropathic pain. Its mechanism was discussed by comparing the efficacy between acupuncture and artificial tears.

Enrollment

20 patients

Sex

All

Ages

20 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

According to the DEWS diagnostic criteria, the OSDI score ≥ 13, with positive signs of dry eye (SIt ≤ 10mm/5min or TBUT ≤ 10s) or CFS positive;
VAS>0;
Signed informed consent.

Exclusion criteria

Patients with dry eye who have had irritants directly irritating the ocular surface in the past 3 days;
Eyeball infections, allergies, deformities, abnormal movements
Any history of eye surgery
Have had eye trauma or fundus laser treatment within 3 months
Used drugs that affect tear production such as antihistamines, antidepressants, etc. within 30 days
Suffer from systemic diseases that affect tear production, including Sjogren's syndrome, diabetes, mental illness, malignant tumors, etc.