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Study on Left Atrial Function of Paroxysmal Supraventricular Tachycardia After Radiofrequency Ablation

R

Ruiqin xie

Status

Completed

Conditions

Paroxysmal Supraventricular Tachycardia

Treatments

Procedure: radiofrequency ablation

Study type

Interventional

Funder types

Other

Identifiers

NCT03348436
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Details and patient eligibility

About

This study to investigate the effects of RF ablation on left atrial systolic function in patients with atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular tachycardia (AVRT).

Full description

A total of 100 patients with persistent,in whom successful RF ablation of slow pathway or accessory pathway was performed. Patients with atrial fibrillation, structural heart disease, ventricular arrhythmias, impaired left ventricular systolic function or on antiarrhythmics were excluded. All the patients had echocardiographic study before ablation 、1 day and 1 months after ablation. Left atrial systolic function was assessed using atrial ejection force (AEF) according to Manning's formula (AEF = 0.5 x ρ x MA x A(2), r: blood density = 1.06 g/cm(3), MA: mitral orifice area [cm(2)], A: A wave velocity). The following left atrial dimensions were assessed: antero-posterior (LA-AP), infero-superior (LA-IS, long axis), medio-lateral (LA-ML, short axis). The correlations between AEF and electrophysiological parameters were analysed (VA - ventriculo-atrial conduction, VA/CL - tachycardia cycle length).

Enrollment

100 patients

Sex

All

Ages

14+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with paroxysmal supraventricular tachycardia,includes atrioventricular reentrant tachycardia and atrioventricular nodal reentrant tachycardia, Age is >14 years

Exclusion criteria

Atrial fibrillation, Atrial tachycardia, Structural heart disease, Ventricular arrhythmias, Patients with impaired left ventricular systolic function or on antiarrhythmics

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

100 participants in 2 patient groups

patients with atrioventricular nodal reentrant tachycardia
Experimental group
Description:
radiofrequency catheter ablation therapy
Treatment:
Procedure: radiofrequency ablation
patients with atrioventricular tachycardia
Experimental group
Description:
radiofrequency catheter ablation therapy
Treatment:
Procedure: radiofrequency ablation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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