Study on Post-Acute COVID-19 Syndrome in Improvement of COVID-19 Rehabilitated Patients by Respiratory Training

Tri-Service General Hospital

Status: Completed

Conditions: COVID-19; Dyspnea; Post-Acute COVID-19 Syndrome; Incentive Spirometer

Treatments: Device: breathing training

Study type: Interventional

Funder types: Other

Identifiers

NCT06165835

A202305044

Details and patient eligibility

About

Since the emergence of Corona Virus Disease 2019(COVID-19), it has spread rapidly around the world, And it has had a profound impact on the lives and health of people around the world, most of the COVID-19 positive patients are 3-4 weeks after the onset of infection patients can turn negative and recover, however, increasing observational data suggest that these patients long-term or recurring symptoms such as: fatigue, palpitations, cognitive impairment, dyspnea, anxiety, chest tightness and Pain, etc., symptoms may last at least two months or even longer (for example, up to 12 months), the patient's quality of life and The ability to work and social activities also decline accordingly. Therefore, in addition to the acute symptoms after infection, patients also face the same. The challenge of long-term health sequelae associated with COVID-19.

Full description

Relevant studies have shown that breathing training can improve the exercise capacity, lung function, and respiratory rate of patients who have recovered from COVID-19. Difficult and other aspects are safe and effective. However, because COVID-19 is an emerging disease, the clinical research literature so far has limited Clinical data are still insufficient, and the effect of respiratory training on the breathing and physical function of COVID-19 patients has not been determined, and most of the patients are not living in the hospital. How to carry out simple and effective breathing training to reduce the long-term impact of COVID-19 on patients is worthy of continuous discussion. This study will assist COVID-19 patients to perform respiratory training with incentive spirometer intervention, and collect patients before and after the intervention Oxygen requirements, blood draw values and Post-COVID-19 Functional Status scale(PCFS scale) and other data to explore and evaluate the effect of interventional breathing training on the improvement of symptoms of new coronary pneumonia, as a reference for future clinical treatment and improvement of symptoms of COVID-19.

Enrollment: 90 patients

Sex: All

Ages: 20 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients who have recovered from COVID-19

Exclusion criteria

1. Have suffered from within one year. Those who have recovered from COVID-19 must present proof of diagnosis, such as a medical certificate or screening results, etc., and ICD10 when seeking medical treatment The diagnostic codes are: U07.1 Confirmed COVID-19 virus infection, U09.0 Severe specific infectious pneumonia (COVID-19), unspecified.
2. adult, aged 20-90
3. conscious mind and behavior normal mental state examination (Mini-Mental State Examination, MMSE) score > 21 points.
4. Those who can communicate in verbal or non-verbal ways and understand Chinese and Taiwanese.
5. are willing to participate in the research and agree to accept random machine dispatcher

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 5 patient groups

Experimental

No Intervention group

Description:

Patients who have recovered from COVID-19

Three months after recovering from COVID-19

Experimental group

Description:

Patients who have from COVID-19 in three months

Treatment:

Device: breathing training

Six months after recovering from COVID-19

Experimental group

Description:

Patients who have from COVID-19 in three to six months

Treatment:

Device: breathing training

Nine months after recovering from COVID-19

Experimental group

Description:

Patients who have from COVID-19 in six to nine months

Treatment:

Device: breathing training

Twelve months after recovering from COVID-19

Experimental group

Description:

Patients who have from COVID-19 in nine to twelve months

Treatment:

Device: breathing training