Study on Screening Strategies for Interstitial Lung Abnormalities and Airway Lesions (SSILA)

China-Japan Friendship Hospital

Status: Not yet enrolling

Conditions: Interstitial Lung Abnormalities

Study type: Observational

Funder types: Other

Identifiers

NCT07023575

2024ZD0522301

Details and patient eligibility

About

The goal of this observational study is to learn about the comorbidity patterns of interstitial and airway abnormalities in adults undergoing health examinations in China. The main questions it aims to answer are:

How do early interstitial lung abnormalities progress to comorbid interstitial and airway diseases? What are the key factors associated with this progression?

Participants undergoing routine health examinations will be assessed for interstitial and airway abnormalities based on imaging and clinical data. Longitudinal follow-up will be used to evaluate disease progression and identify associated risk factors.

Enrollment: 100,000 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Underwent chest CT examination between January 1, 2017 and December 31, 2024
• Age 18 years or older at the time of examination

Exclusion criteria

• Missing or incomplete key demographic or imaging information (e.g., missing date of examination, sex, age, or CT report)

Trial design

100,000 participants in 1 patient group

Chinese Routine Chest CT Health Examination Cohort

Description:

This group includes individuals who underwent routine health examinations with chest CT imaging at participating health checkup centers across China between 2017 and 2024. Participants may have one or more CT records, and no interventions were applied as part of the study. This group will be analyzed for the presence of interstitial lung abnormalities and/or airway diseases based on imaging and lung function data, as well as demographic and clinical characteristics.