Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation

National Center for Cardiovascular Diseases

Status: Completed

Conditions: Mitral Valve Insufficiency; Mitral Valve Annuloplasty; Coronary Artery Bypass

Treatments: Procedure: mitral valve repair

Study type: Observational

Funder types: Other

Identifiers

NCT06408779

m_IMR_2024

Details and patient eligibility

About

This study aimed to compare the efficacy of isolated coronary artery bypass grafting and coronary artery bypass grafting + mitral valve repair in moderate ischemic mitral regurgitation patients through a cohort and explore the potential risk factors of the clinical outcomes.

Enrollment: 464 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adult coronary artery disease patients complicated with moderate ischemic mitral regurgitation.
2. undergoing coronary artery bypass grafting with or without mitral valve repair.

Exclusion criteria

1. patients under the age of 18 years,
2. patients complicated with more than moderate ischemic mitral regurgitation or undergoing mitral valve replacement,
3. patients complicated with primary mitral valve disease other than ischemic mitral regurgitation, such as rheumatic mitral regurgitation or mitral valve leaflet prolapse,
4. patients undergoing concomitant aortic valve procedure.

Trial design

464 participants in 2 patient groups

coronary artery bypass grafting

Treatment:

Procedure: mitral valve repair

coronary artery bypass grafting concomitant mitral valve repair

Treatment:

Procedure: mitral valve repair