Study on Susceptibility Genes of Anterior Cruciate Ligament, Patella Dislocation and Discoid Meniscus

Peking University

Status: Enrolling

Conditions: Cruciate Ligament Rupture; Gene Abnormality; Meniscus Injury

Study type: Observational

Funder types: Other

Identifiers

NCT04997538

IRB00006761-M2018245

Details and patient eligibility

About

Genomes of all sports medicine-related genes will be exome sequenced to find relevant gene mutations. To further study the molecular mechanisms and signaling pathways related to sports injury. To search for genetic risk factors of injury and put forward related scientific hypotheses. To demonstrate the importance of mutation or polymorphism of related genes in injury.

Enrollment: 3,000 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with joint sports injuries.
2. Follow-up patients after sports injury.
3. Patients with genetic predisposition to sports injuries.
4. Patients with family genetic predisposition to exercise-related diseases and their relatives.

Exclusion criteria

1. Patients with joint damage caused by external force.
2. The patient is accompanied by other injuries at the same time.