Study on the Accuracy of Determining the Responsible Vessel in Medium Vessel Occlusive Stroke Based on Multi-type CT Evaluation

Capital Medical University

Status: Enrolling

Conditions: Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT07347587

XMEC-2025-001

Details and patient eligibility

About

To evaluate the accuracy of diagnosing the qualifying artery in patients with medium vessel occlusion stroke based on multimodal CT

Enrollment: 622 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with acute ischemic stroke, without restrictions on gender
• Age ≥ 18 years old
• The time from onset to treatment is within 24 hours (the onset time is defined as the "last-well-time", and the treatment plan is determined according to the patient's wishes and local clinical experience)
• Before the treatment, CT, CTA and CTP examinations were conducted, and the relevant clinical data were complete.

Exclusion criteria

• Patients with acute intracranial hemorrhage
• Patients whose CTP original images cannot be processed by the CTP post-processing software
• Patients for whom the DICOM format image data of CT, CTP original images and MRI images cannot be obtained, or whose image quality is poor due to various reasons

Trial design

622 participants in 2 patient groups

NCCT+CTA group

Description:

The attending physicians of neurology (with more than 5 years of experience in neuroimaging interpretation and not relevant to this study), without knowing the final radiological report, DSA, MRI results and clinical manifestations, only used baseline non-contrast CT (NCCT) and CTA to determine whether the included cases had moderate vascular occlusion. And record the qualifying artery

NCCT+CTA+CTP group

Description:

The attending physicians of neurology (with more than 5 years of experience in neuroimaging interpretation and not relevant to this study), without knowing the final radiological report, DSA, MRI results and clinical manifestations, only used baseline non-contrast CT (NCCT) , CTA and CTP to determine whether the included cases had moderate vascular occlusion. And record the qualifying artery