Study on the Difference of Preoperative Related Parameters in Children With or Without Microcornea Within Less Than One Year Old

Wenzhou Medical University

Status: Completed

Conditions: Microcornea Within One Year of Age

Treatments: Device: Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth

Study type: Observational

Funder types: Other

Identifiers

NCT04852341

Microcornea

Details and patient eligibility

About

This subject is mainly to study difference of Congenital cataract preoperative related parameters in children with or without Microcornea within Less than one year old. A total of 186 eyes of 117 people were collected with relevant ocular biological parameters, including age, horizontal diameter of the cornea, Eye axis, intraocular pressure, steep axis of corneal curvature, flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth. At present, because the definition of patients with small cornea is not clear enough, the study subjects are divided into 4 groups according to the horizontal corneal diameter of 9.0mm, 9.5mm, and 10.0mm, namely ≤9.0mm group, 9~9.5mm group, 9.5~10.0mm group and The >10.0mm group compares the differences between each other, and tries to provide a reference for the diagnosis of children with small cornea at a young age.

Enrollment: 117 patients

Sex: All

Ages: 1 to 12 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Congenital cataract children with or without Microcornea within Less than one year old
• Complete collection of eye biological parameters before the first-stage Congenital cataract surgery
• The nutritional status and development of the included subjects have no obvious defects

Exclusion criteria

• congenital persistent pupilary membrane
• lens sublaxation or lens dislocotion
• Marfan syndrome
• Down's Syndrome
• Peters abnormality
• Fevr
• history of obvious eye trauma
• obvious macula
• long-term (local or systemic) use of glucocorticoids.

Trial design

117 participants in 4 patient groups

Corneal horizontal diameter ≤9.00mm group

Treatment:

Device: Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth

Corneal horizontal diameter 9.00mm~9.50mm group

Treatment:

Device: Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth

Corneal horizontal diameter 9.50mm~10.00mm group

Treatment:

Device: Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth

Corneal horizontal diameter >10.00mm group

Treatment:

Device: Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth