Study on the Effect Mechanism of Acupuncture Combined With Swallowing Training in Oral Dysphagia of Stroke

Qingqing Zhang

Status: Not yet enrolling

Conditions: Dysphagia; Stroke; Oral Phase

Treatments: Other: Acupuncture; Behavioral: Conventional rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT05982977

2022J01880

Details and patient eligibility

About

Up to 84% of patients after stroke are accompanied by dysphagia, of which 53% are oral dysphagia. The oral phase is the initial phase of swallowing activity and the only stage of swallowing that is completely discretionary. Swallowing activity in the oral stage is not only related to the formation and push of food pellets, but also affects the continuity between the transition from spontaneous swallowing to the swallowing reflex.

Full description

After stroke, patients are prone to oral dysphagia, poor control of food masses and liquids in the mouth, resulting in food spillover, residual and premature overflow, resulting in dehydration, malnutrition, aspiration, pneumonia and other serious consequences, which greatly reduce the eating safety and quality of life of patients after stroke. Therefore, the rehabilitation of oral swallowing function is a way for patients with swallowing disorder after stroke to return to society and improve their quality of life. Previous studies have found that acupuncture is an effective intervention to improve swallowing disorder in oral stage after stroke. Whether acupuncture promotes the improvement of swallowing function in oral stage by regulating the synergic activity of cortical swallowing network and muscle group has not been fully clarified.

Enrollment: 56 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients meeting the diagnostic criteria for acute ischemic stroke established by the Neurology Society of the Chinese Medical Association and confirmed by craniocerebral CT or MRI;
2. Oral dysphagia caused by stroke;
3. Currently diet is restricted, FOIS score is 5 or less; WST score 3 or above;
4. MoCA score of 21 or above, able to understand and follow simple instructions from the treatment staff, able to cooperate and willing to undergo examination and treatment;
5. 40 to 75 years old;
6. Conscious and stable vital signs;
7. Convalescent patients with stroke course and dysphagia duration between 1-6 months;
8. Voluntary participation and informed consent.

Exclusion criteria

1. Patients with dysphagia not caused by stroke or non-stroke oral dysphagia;
2. Previous history of stroke or dysphagia;
3. Patients with serious primary diseases or mental disorders of other systems;
4. Suffering from various bleeding prone diseases;
5. Severe needle fainting;
6. People with metal implants.
7. Patients with poor compliance are not treated as prescribed

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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56 participants in 2 patient groups

Acupuncture rehabilitation group

Experimental group

Description:

Acupuncture rehabilitation intervention was given on the basis of conventional rehabilitation therapy.Disinfected with 75% alcohol and applied the needles at a depth of 25-35mm. Acupuncture stimulation of Lianquan (CV23) and Fengchi (GB20). The needles were retained for 30 minutes/time, once a day, and 5 days/week for a total of 4 weeks.

Treatment:

Other: Acupuncture

Conventional rehabilitation group

Active Comparator group

Description:

This group participants would take swallowing training 30 minutes/time, once a day, 5 days/week, a total of 4 weeks of intervention. At the same time, stroke basic treatment, nutritional support and other symptomatic treatment

Treatment:

Behavioral: Conventional rehabilitation