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Study on the Effect of Fish Oil and Appetite

A

AAstrup

Status and phase

Completed
Early Phase 1

Conditions

Cachexia
Obesity

Treatments

Dietary Supplement: Fish oil

Study type

Interventional

Funder types

Other

Identifiers

NCT01692990
LL-spec1

Details and patient eligibility

About

20 normal-weight healthy subjects (10 males, 10 females) were in two periods given 10 of 0.5-mL capsules/day of fish oil and soybean oil for 3 weeks. In the end of each period they were given a standard breakfast and asked to report their appetite on visual analogue scales (VAS) immediately before and after the meal. The results were analyzed in accordance with the paired design under consideration of both supplement sequence and gender.

Full description

In a randomized cross-over design, 20 normal-weight healthy subjects (10 males, 10 females) were given 10 of 0.5-mL capsules/day of fish oil and soybean oil for 3 weeks. In the end of each period they were given a standard breakfast and asked to report their appetite on visual analogue scales (VAS) immediately before and after the meal. The results were analyzed in accordance with the paired design under consideration of both supplement sequence and gender.

Enrollment

20 patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Normal weight (18.5<BMI<25 kg/m2).
  • Healthy.

Exclusion criteria

  • Subjects taking medication that could influence appetite.
  • Subjects with special nutritional needs e.g. pregnant and lactating, seriously ill or old people.
  • Subjects that had had fish oil-supplements for four weeks prior to the intervention period.

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Quadruple Blind

20 participants in 2 patient groups, including a placebo group

Fish oil
Experimental group
Description:
5 g/d in 10 capsules, providing 3.5 g of long-chain n-3 fatty acids
Treatment:
Dietary Supplement: Fish oil
Soy bean oil
Placebo Comparator group
Description:
5 g/d in 10 capsules
Treatment:
Dietary Supplement: Fish oil

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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