Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis

Capital Medical University

Status: Unknown

Conditions: Selenium

Treatments: Drug: Selenium

Study type: Interventional

Funder types: Other

Identifiers

NCT04942769

2021-310

Details and patient eligibility

About

To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.

Full description

In patients with autoimmune thyroiditis， investigators compared changes in thyroid function, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, thyroid magnetic resonance T1-mapping values and metabolic indicatorsfrom baseline to the end of treatment (12 weeks)

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men or women between the ages of 18 and 75
• Clinical diagnosis of autoimmune thyroiditis, serum TPOAb and TGAB positive
• Thyroid function is normal, and no drugs affecting thyroid function such as Umetole and Serge have been used

Exclusion criteria

• The contraindications indicated in the Chinese instructions of the drug
• Hypothyroidism, hyperthyroidism
• Liver function impairment
• Renal function impairment
• Claustrophobia
• Mental disorders

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

selenium

Experimental group

Description:

selenium was administered to patients with autoimmune thyroiditis

Treatment:

Drug: Selenium