Study on the Effects of a Recommendation Based Supply of Vitamin D3 in Healthy Volunteers

Martin-Luther-Universität Halle-Wittenberg

Status: Completed

Conditions: Deficiency of Vitamin D3

Treatments: Dietary Supplement: Vitamin D3

Study type: Interventional

Funder types: Other

Identifiers

NCT01711905

0315668

Details and patient eligibility

About

The aim of this study is to investigate whether a supplementation of 20 µg Vitamin D3 per day for 12 weeks can be used to normalize vitamin d-Status

Full description

It is the objective of this study to investigate whether a supplementation with Vitamin D3 can be used to normalize insufficient vitamin d status and reduce atherosclerotic risk factors such as hypertension, inflammation and hyperlipidemia. The research question is whether Vitamin D3 reduces the level of systemic inflammation and whether Vitamin D3 has an effect on blood lipids.

Enrollment: 107 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers
• age between 18 and 70 years
• informed consent

Exclusion criteria

• use of antihypertensive medication
• use of vitamin d or calcium supplements
• known renal, inflammatory or malignant diseases
• hypercalcemia or hypercalciuria
• participation in other clinical studies
• use of tanning booths during the study
• pregnancy or lactating period

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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107 participants in 2 patient groups

Vitamin D3

Experimental group

Description:

cholecalciferol 20 µg per day for 12 weeks

Treatment:

Dietary Supplement: Vitamin D3

Placebo

No Intervention group

Description:

Placebo for 12 weeks