Study on the Protective Effect of Gastrodin on Myocardial Injury in Patients Undergoing Cardiac Surgery

Huazhong University of Science and Technology

Status: Enrolling

Conditions: Cardiac Surgical Procedures

Study type: Observational

Funder types: Other

Identifiers

NCT06012968

mzk202301

Details and patient eligibility

About

This study intends to include hypertrophic cardiomyopathy patients over 18 years old who underwent cardiac surgery in our hospital. Patients were divided into medication group and control group according to the use of gastrodin during operation. The patients ' myocardial tissue samples were collected, the postoperative prognosis data were observed and recorded, and the data were analyzed. The degree of myocardial tissue cell damage and postoperative clinical outcomes were compared between the two groups.

Enrollment: 10 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with hypertrophic cardiomyopathy aged≥18 years, regardless of gender;
• Patients undergoing elective hypertrophic cardiomyopathy outflow tract surgery;
• Signed informed consent, good compliance.

Exclusion criteria

• suffering from more serious genetic diseases (such as immunodeficiency, thalassemia, etc.);
• moderate to severe malnutrition, moderate to severe anemia;
• persistent infection;
• severe preoperative underlying diseases (such as severe liver and kidney dysfunction)

Trial design

10 participants in 2 patient groups

GAS

Control