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Study on the Protective Effect of RIPC in Patients Undergoing Cardiac Surgery.

Fudan University logo

Fudan University

Status

Completed

Conditions

Cardiac Surgery

Treatments

Device: RIPC

Study type

Interventional

Funder types

Other

Identifiers

NCT04433468
2020RIPC

Details and patient eligibility

About

To observe the effect of RIPC on the function of vital organs after cardiac surgery, and to explore its possible mechanism.

Enrollment

60 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with aortic valve, mitral valve, tricuspid valve, ascending aortic disease and coronary atherosclerosis who were admitted to hospital for elective valve repair, replacement, artificial vascular replacement or coronary artery bypass grafting.
  • age 18-80 years old.
  • No restriction on gender.
  • ASA grade II~III.
  • NYHAII~III level.
  • the patient or his family member has signed the informed consent form for the clinical trial

Exclusion criteria

  • those who are disabled in the selected test.
  • less than 5 years of education.
  • The preoperative left ventricular ejection fraction ((LVEF)) was less than 40%.
  • Myocardial infarction occurred in nearly one month.
  • malignant tumor, hematological disease, severe liver and kidney dysfunction, recent severe infection, etc.
  • History of nervous system, immune system and mental illness.
  • recent operation history of heart, brain, lung, liver, kidney and other important organs

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

60 participants in 2 patient groups

RIPC
Active Comparator group
Treatment:
Device: RIPC
Control
No Intervention group

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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