Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application

Sanford Health

Status and phase

Unknown

Phase 4

Conditions

Bacterial Colonization

Surgical Site Infection

Lower Extremity Surgery

Surgical Antiseptic

Treatments

Drug: Chloraprep

Study type

Interventional

Funder types

Other

Identifiers

NCT02017145

SH Chloraprep reapplication

Details and patient eligibility

About

The purpose of the current work is to determine the efficacy of the re-application of surgical prep solution in decreasing surgical site bacterial contamination following lower extremity surgery. Decreasing the extent of bacterial colonization of the skin surrounding the surgical site during the initial healing phases would theoretically decrease the rate of infection in high-risk persons.

Enrollment

140 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male and female
Adults (18+)
Both elective and non-elective procedures
Lower extremity surgery performed below the knee and requiring post-operative splint immobilization for 2-3 weeks
Able to understand and read the English language
Signed informed consent

Exclusion criteria

Pregnant (to be assessed the day of surgery per standard of care surgical protocol)
Known allergies to chlorhexidine gluconate or isopropyl alcohol
Multiple planned lower extremity surgeries
Local skin disease
Pre-existing or known infection at surgical site
Open wounds or local abrasions
Unable to or unwilling to follow through with study requirements