Study on the Response to Tetanus Vaccination of People Living With HIV (VACTEVIH)

Centre Hospitalier de Niort

Status: Completed

Conditions: HIV Infections

Treatments: Diagnostic Test: additional blood sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT03853681

PI-2019-02

Details and patient eligibility

About

The response to primary tetanus immunization of HIV-infected children is lower than that of uninfected children.

Response to tetanus toxoid (TT) booster doses in adults living with HIV who have received primary vaccination prior to infection is not known.

Currently, it is recommended to have a TT booster for people living with HIV (PLHIV) every 10 years. In general population, this recall is made only at 25, 45 and 65 years, then every 10 years.

Enrollment: 210 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Person aged ≥ 18 years
• Person infected with HIV followed in the infectious diseases department of CH Niort
• Born in France
• Affiliate or beneficiary of a social security scheme
• Being able to give free and informed consent to participation in research

Exclusion criteria

• Persons with a contraindication to tetanus vaccination
• Persons under guardianship or curatorship or without civil law

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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210 participants in 1 patient group

additional blood sampling

Other group

Treatment:

Diagnostic Test: additional blood sampling