Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer

Yunnan Cancer Hospital

Status

Enrolling

Conditions

Gastric Cancer

Treatments

Diagnostic Test: Scanning parameter

Study type

Interventional

Funder types

Other

Identifiers

NCT06735105

KYLX2023-167

Details and patient eligibility

About

Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.

This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients.

A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.

Enrollment

129 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

The patient was diagnosed with gastric cancer by pathological biopsy
No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.

Exclusion criteria

The image quality cannot meet the diagnostic criteria;
Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.