Study Project Comparing the Sequelae of COVID-19 Infection in Patients Who Have and Have Not Received Ventilatory Support in Critical Care (COMEBAC)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Covid19

Study type: Observational

Funder types: Other

Identifiers

NCT04704388

COMEBAC

Details and patient eligibility

About

To assess the proportion of post-intensive care syndrome (PICS) of patients who received high flow humidified oxygen with FiO2 ≥50% for more than 48h and / or who received mechanical ventilation for more than 48h in a context of hospitalization in intensive care for COVID-19 pneumonia

Enrollment: 478 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Group 1: patients hospitalized in intensive care units for ARDS with SARS-CoV-2

• Major
• Admitted between March 1 and May 10, 2020 in one of the sectors of the Bicêtre hospital approved for critical care
• proven SARS-CoV-2 infection
• Treated by invasive mechanical ventilation or high flow humidified oxygen with FiO2 ≥50% for more than 48 hours.

Group 2: patients hospitalized outside intensive care units

• Major
• Admitted between March 1 and May 10, 2020 in an area of Bicêtre hospital having cared for patients infected with SARS-CoV-2 excluding critical care: pulmonology, internal medicine / orthopedics, infectious diseases, nephrology , acute geriatrics, neurology.

Exclusion criteria

• Patients having refused the post consultation at 3 month
• Without social security coverage

Trial design

478 participants in 2 patient groups

patients hospitalized in intensive care units for SARS-CoV-2

Description:

patients hospitalized in intensive care units for SARS-CoV-2

patients hospitalized outside intensive care units

Description:

patients hospitalized outside intensive care units