Study the Safety and Efficacy of "Compont Medical Glue" in the Treatment of Esophagogastric Varices

Fudan University

Status: Unknown

Conditions: Esophageal and Gastric Varices

Study type: Observational

Funder types: Other

Identifiers

NCT02945930

CSY-2016-ZZJ

Details and patient eligibility

About

To observe the Safety and Efficacy of Compont Medical Glue in the Treatment of Esophagogastric Varices.

Full description

"Compont Medical Glue" is a kind of histoacryl producted by Compont Company. It has been used to treat esophagogastric varices for several years. This study is a prospective multicenter,open study on the safety and efficacy of Compont Medical Glue in the treatment of esophagogastric varices. Weather the patient receiving injection of Compont Medical Glue is according to the degree of esophageal-gastric varices and is decided by the experienced endoscopic physicians. No additional intervention will be given to the patients, no matter whether patients are participated in the study.

Enrollment: 2,200 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Esophagogastric varices caused by portal hypertension with or without history of bleeding and no matter whether emergency bleeding.
• Patients may need to receive injection of histoacryl.
• Have signed informed consent.

Exclusion criteria

• Allergic to formaldehyde or cyanoacrylate.
• Women who are pregnant or breast-feeding.
• With contraindications of endoscopic exam.
• Computed tomography(CT)/Computed tomography angiography(CTA) shows that patient with severe portosystemic shunt.
• Large amount of blood accumulated in the stomach severely affects the endoscopic vision clarity.
• Other reasons that researcher think the patient is unsuitable for participating in the study.